- Introduction Caroline Kennedy
- Foreword Robert F. Kennedy
- Preface
- Courage and Politics
- John Quincy Adams
- Daniel Webster
- Thomas Hart Benton
- Sam Houston
- Edmund G. Ross
- Lucius Quintus Cincinnatus Lamar
- George Norris
- Robert A. Taft
- Other Men of Political Courage
- The Meaning of Political Courage
P.S.: Insights, Interviews & More
- Biography of John F. Kennedy
- Correspondence: JFK on Profiles
- The Contemporary Take: Excerpts from Reviews of Profiles in Courage
- Letter from Ernest Hemingway to JFK
- The John F. Kennedy Profile in Courage Award
- In Their Own Words: Recipients of the Profile in Courage Award
- Have You Read? Also by John F. Kennedy
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